Usp30 | ubiquitin specific peptidase 30

GeneMGI:2140991Synonyms: D5Ertd483e, 6330590F17Rik

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Hearing/vestibular/ear Hematopoietic system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



thrombocytopenia	1 supporting dataset	Usp30^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	3.7x10^-5
abnormal auditory brainstem response	2 supporting datasets	Usp30^{em1(IMPC)Marc}	homozygote	Early adult	1.13x10^-6
impaired glucose tolerance	1 supporting dataset	Usp30^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	2.83x10^-6
increased circulating alkaline phosphatase level	1 supporting dataset	Usp30^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	9.75x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Usp30.

Associated images

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Histopathology

There is no histopathology data found for Usp30.

IMPC related publications

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External links

No external links available for Usp30.

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*Usp30^{em1(IMPC)Marc}*	Deletion	‌	mouse
*Usp30^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Usp30^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Usp30^{tm2b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Usp30^{tm2c(EUCOMM)Hmgu}*	Wild type floxed exon (post-Flp)	‌	mouse
*Usp30^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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