Fam185a | family with sequence similarity 185, member A

Physiological systems

21 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Respiratory system Hematopoietic system Behavior/neurological Cardiovascular system

11 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal heart morphology	1 supporting dataset	Fam185a^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
hydrometra	1 supporting dataset	Fam185a^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased lung tissue damping	2 supporting datasets	Fam185a^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.88x10^-5
abnormal skin morphology	1 supporting dataset	Fam185a^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased circulating creatinine level	1 supporting dataset	Fam185a^{em1(IMPC)Ccpcz}	homozygote	Early adult	6.98x10^-5
enlarged heart	1 supporting dataset	Fam185a^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased circulating sodium level	1 supporting dataset	Fam185a^{em1(IMPC)Ccpcz}	homozygote	Early adult	9.15x10^-5
abnormal thymus morphology	1 supporting dataset	Fam185a^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Fam185a^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased startle reflex	1 supporting dataset	Fam185a^{em1(IMPC)Ccpcz}	homozygote	Early adult	9.23x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fam185a.

Associated images

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Histopathology

There is no histopathology data found for Fam185a.

IMPC related publications

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External links

No external links available for Fam185a.

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*Fam185a^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Fam185a^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Fam185a^{tm44036(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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