Slc44a1 | solute carrier family 44, member 1

GeneMGI:2140592Synonyms: 4833416H08Rik, CHTL1, +3 more

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Integument Nervous system Vision/eye Behavior/neurological Skeleton Cardiovascular system

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

1Associated diseases

Expression examined in:51Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased prepulse inhibition	2 supporting datasets	Slc44a1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.28x10^-7
increased vertical activity	1 supporting dataset	Slc44a1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7x10^-9
irregularly shaped pupil	1 supporting dataset	Slc44a1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.02x10^-5
increased bone mineral content	1 supporting dataset	Slc44a1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3x10^-5
abnormal coat appearance	3 supporting datasets	Slc44a1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.43x10^-12
abnormal retina blood vessel morphology	1 supporting dataset	Slc44a1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.07x10^-5
abnormal retina outer nuclear layer morphology	2 supporting datasets	Slc44a1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	0
abnormal bone structure	1 supporting dataset	Slc44a1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.71x10^-5
hyperactivity	1 supporting dataset	Slc44a1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.11x10^-6
abnormal eye posterior chamber depth	1 supporting dataset	Slc44a1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.36x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Slc44a1.

Associated images

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Histopathology

There is no histopathology data found for Slc44a1.

IMPC related publications

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External links

No external links available for Slc44a1.

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*Slc44a1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Slc44a1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Slc44a1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Slc44a1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Slc44a1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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