Pramel12 | PRAME like 12

GeneMGI:2140473Synonyms: 4732496O08Rik, Pramef8

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Digestive/alimentary Vision/eye Hematopoietic system Renal/urinary system

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:15Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal urinary bladder morphology	1 supporting dataset	Pramel12^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged spleen	2 supporting datasets	Pramel12^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Pramel12^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Pramel12^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal kidney morphology	2 supporting datasets	Pramel12^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal cecum morphology	1 supporting dataset	Pramel12^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Pramel12^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
small kidney	1 supporting dataset	Pramel12^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal jejunum morphology	1 supporting dataset	Pramel12^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal duodenum morphology	1 supporting dataset	Pramel12^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pramel12.

Associated images

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Histopathology

There is no histopathology data found for Pramel12.

IMPC related publications

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External links

No external links available for Pramel12.

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*Pramel12^em1(IMPC)Mbp*	Intra-exon deletion	‌	mouse
*Pramel12^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pramel12^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Pramel12^{tm43951(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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