Slc35d1 | solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1

GeneMGI:2140361Synonyms: UGTREL7

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Embryo Growth/size/body region Limbs/digits/tail Digestive/alimentary Mortality/aging Craniofacial

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:51Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Slc35d1^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
edema	1 supporting dataset	Slc35d1^{tm2b(EUCOMM)Hmgu}	homozygote	E18.5	N/A ^*
abnormal tail morphology	1 supporting dataset	Slc35d1^{tm2b(EUCOMM)Hmgu}	homozygote	E18.5	N/A ^*
abnormal facial morphology	2 supporting datasets	Slc35d1^{tm2b(EUCOMM)Hmgu}	homozygote	E18.5	N/A ^*
abnormal embryo size	1 supporting dataset	Slc35d1^{tm2b(EUCOMM)Hmgu}	homozygote	E18.5	N/A ^*
cleft palate	1 supporting dataset	Slc35d1^{tm2b(EUCOMM)Hmgu}	homozygote	E18.5	N/A ^*
abnormal limb morphology	1 supporting dataset	Slc35d1^{tm2b(EUCOMM)Hmgu}	homozygote	E18.5	N/A ^*
protruding tongue	1 supporting dataset	Slc35d1^{tm2b(EUCOMM)Hmgu}	homozygote	E18.5	N/A ^*
abnormal coat appearance	1 supporting dataset	Slc35d1^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	4.64x10^-5
abnormal head shape	1 supporting dataset	Slc35d1^{tm2b(EUCOMM)Hmgu}	homozygote	E18.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Slc35d1.

Associated images

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Histopathology

There is no histopathology data found for Slc35d1.

IMPC related publications

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External links

No external links available for Slc35d1.

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*Slc35d1^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Slc35d1^{tm2b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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