H6pd | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)

GeneMGI:2140356Synonyms: Gpd1, G6pd1, +1 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased startle reflex	1 supporting dataset	H6pd^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.06x10^-6
increased circulating aspartate transaminase level	1 supporting dataset	H6pd^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.48x10^-6
abnormal locomotor activation	1 supporting dataset	H6pd^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.78x10^-5
decreased circulating alkaline phosphatase level	1 supporting dataset	H6pd^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.8x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for H6pd.

Associated images

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Histopathology

There is no histopathology data found for H6pd.

IMPC related publications

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External links

No external links available for H6pd.

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*H6pd^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*H6pd^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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