Phactr4 | phosphatase and actin regulator 4

GeneMGI:2140327Synonyms: 3110001B12Rik, C330013F19Rik

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Mortality/aging Cardiovascular system

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetPhactr4em1(IMPC)HmguhomozygoteEarly adultN/A * 
abnormal QT variability1 supporting datasetPhactr4em1(IMPC)HmguheterozygoteEarly adult6.22x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Phactr4em1(IMPC)HmguIntra-exon deletionmouse
Phactr4tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Phactr4tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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