Ints3 | integrator complex subunit 3
GeneMGI:2140050
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Hematopoietic system Behavior/neurological Mortality/aging
15 No significant impact
6 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal vocalization | 1 supporting dataset | Ints3em1(IMPC)J | heterozygote | Early adult | 2.42x10-10 | ||
| decreased mean corpuscular hemoglobin | 1 supporting dataset | Ints3em1(IMPC)J | heterozygote | Early adult | 5.98x10-6 | ||
| increased aggression | 1 supporting dataset | Ints3em1(IMPC)J | heterozygote | Early adult | 8.07x10-6 | ||
| increased grip strength | 1 supporting dataset | Ints3em1(IMPC)J | heterozygote | Early adult | 1.49x10-6 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Ints3em1(IMPC)J | homozygote | E9.5 | N/A * | ||
| decreased mean corpuscular volume | 1 supporting dataset | Ints3em1(IMPC)J | heterozygote | Early adult | 9.16x10-5 | ||
| abnormal locomotor behavior | 1 supporting dataset | Ints3em1(IMPC)J | heterozygote | Early adult | 1.39x10-5 | ||
| increased erythrocyte cell number | 1 supporting dataset | Ints3em1(IMPC)J | heterozygote | Early adult | 4.61x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Ints3em1(IMPC)J | homozygote | Early adult | N/A * |
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External links
No external links available for Ints3.
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| Ints3em1(IMPC)J | Exon Deletion | | mouse |
| Ints3tm401683(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |