Med12l | mediator complex subunit 12-like

GeneMGI:2139916

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Vision/eye Behavior/neurological

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



irregularly shaped pupil	1 supporting dataset	Med12l^em1(IMPC)J	homozygote	Early adult	1.32x10^-6
increased circulating alanine transaminase level	1 supporting dataset	Med12l^em1(IMPC)J	homozygote	Early adult	1.71x10^-9
abnormal coat/hair pigmentation	1 supporting dataset	Med12l^em1(IMPC)J	homozygote	Early adult	1.56x10^-10
abnormal locomotor behavior	1 supporting dataset	Med12l^em1(IMPC)J	homozygote	Early adult	1.33x10^-8
abnormal vocalization	1 supporting dataset	Med12l^em1(IMPC)J	homozygote	Early adult	3.75x10^-9
decreased grip strength	1 supporting dataset	Med12l^em1(IMPC)J	homozygote	Early adult	6.42x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Med12l.

Associated images

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Histopathology

There is no histopathology data found for Med12l.

IMPC related publications

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External links

No external links available for Med12l.

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*Med12l^em1(IMPC)J*	Exon Deletion	‌	mouse
*Med12l^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Med12l^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Med12l^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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