Spart | spartin

GeneMGI:2139806Synonyms: TAHCCP1, Spg20

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging Cardiovascular system

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Spart^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
decreased exploration in new environment	1 supporting dataset	Spart^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	3.2x10^-5
dilated aorta	1 supporting dataset	Spart^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	1.39x10^-5
increased fasting circulating glucose level	1 supporting dataset	Spart^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	4.89x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Spart.

Associated images

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Histopathology

There is no histopathology data found for Spart.

IMPC related publications

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External links

No external links available for Spart.

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*Spart^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Spart^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Spart^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Spart^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Spart^{tm2b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Spart^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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