Sec24b | SEC24 homolog B, COPII coat complex component
Physiological systems
20 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Immune system Embryo Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Hematopoietic system Mortality/aging Craniofacial
11 No significant impact
4 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
abnormal tail morphology | 1 supporting dataset | Sec24bem1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
abnormal eye morphology | 1 supporting dataset | Sec24bem1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
abnormal embryo size | 1 supporting dataset | Sec24bem1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
enlarged lymph nodes | 1 supporting dataset | Sec24bem1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Sec24bem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
exencephaly | 1 supporting dataset | Sec24bem1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
enlarged spleen | 1 supporting dataset | Sec24bem1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
abnormal head shape | 1 supporting dataset | Sec24bem1(IMPC)Tcp | homozygote | E15.5 | N/A * |
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External links
No external links available for Sec24b.
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Sec24bem1(IMPC)Tcp | Exon Deletion | | mouse |
Sec24btm119299(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
Sec24btm119299(L1L2_Pgk_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
Sec24btm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |