Dpyd | dihydropyrimidine dehydrogenase

GeneMGI:2139667Synonyms: DPD, E330028L06Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Reproductive system Digestive/alimentary Behavior/neurological

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



hyperactivity	1 supporting dataset	Dpyd^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.36x10^-6
increased vertical activity	1 supporting dataset	Dpyd^{tm1b(KOMP)Wtsi}	homozygote	Early adult	8.18x10^-6
abnormal stomach morphology	1 supporting dataset	Dpyd^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal epididymis morphology	1 supporting dataset	Dpyd^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dpyd.

Associated images

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Histopathology

There is no histopathology data found for Dpyd.

IMPC related publications

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External links

No external links available for Dpyd.

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*Dpyd^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dpyd^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Dpyd^{tm44438(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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