Prom2 | prominin 2

GeneMGI:2138997

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Vision/eye Hematopoietic system Behavior/neurological

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:52Adult tissues

46Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal retina morphology	1 supporting dataset	Prom2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.19x10^-7
hyperactivity	6 supporting datasets	Prom2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.73x10^-8
decreased grip strength	2 supporting datasets	Prom2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.43x10^-6
abnormal nail morphology	1 supporting dataset	Prom2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.52x10^-5
decreased circulating calcium level	1 supporting dataset	Prom2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	2.95x10^-5
increased circulating alanine transaminase level	1 supporting dataset	Prom2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	5.37x10^-9
abnormal sleep behavior	1 supporting dataset	Prom2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.13x10^-7
increased circulating potassium level	1 supporting dataset	Prom2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	6.22x10^-5
decreased grip strength	1 supporting dataset	Prom2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.89x10^-5
decreased circulating iron level	1 supporting dataset	Prom2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	2.25x10^-11

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Prom2.

Associated images

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Histopathology

There is no histopathology data found for Prom2.

IMPC related publications

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External links

No external links available for Prom2.

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*Prom2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Prom2^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Prom2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Prom2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Prom2^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Prom2^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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