Cdc123 | cell division cycle 123

GeneMGI:2138811Synonyms: G431001I09Rik

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Pigmentation Integument Behavior/neurological Mortality/aging Cardiovascular system

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal coat/hair pigmentation3 supporting datasetsCdc123tm1b(KOMP)WtsiheterozygoteEarly adult5.41x10-7 
preweaning lethality, complete penetrance1 supporting datasetCdc123tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
increased startle reflex1 supporting datasetCdc123tm1b(KOMP)WtsiheterozygoteEarly adult8.5x10-6 
abnormal heart left ventricle morphology1 supporting datasetCdc123tm1b(KOMP)WtsiheterozygoteEarly adult1.62x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cdc123tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Cdc123tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Cdc123tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Cdc123tm359273(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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