Serpinb10 | serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10

Physiological systems

21 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Vision/eye Respiratory system Liver/biliary system Hematopoietic system Cardiovascular system Renal/urinary system

12 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating calcium level	1 supporting dataset	Serpinb10^em1(IMPC)Mbp	homozygote	Early adult	3.57x10^-6
abnormal spleen morphology	1 supporting dataset	Serpinb10^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Serpinb10^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal retina morphology	1 supporting dataset	Serpinb10^em1(IMPC)Mbp	homozygote	Early adult	1.86x10^-7
increased spleen weight	1 supporting dataset	Serpinb10^em1(IMPC)Mbp	homozygote	Early adult	2.45x10^-10
abnormal kidney morphology	1 supporting dataset	Serpinb10^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Serpinb10^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Serpinb10^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal heart shape	1 supporting dataset	Serpinb10^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased circulating triglyceride level	1 supporting dataset	Serpinb10^em1(IMPC)Mbp	homozygote	Early adult	7.83x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Serpinb10.

Associated images

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Histopathology

There is no histopathology data found for Serpinb10.

IMPC related publications

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External links

No external links available for Serpinb10.

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*Serpinb10^em1(IMPC)Mbp*	Exon Deletion	‌	mouse

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