Gigyf2 | GRB10 interacting GYF protein 2

GeneMGI:2138584Synonyms: 2610016F01Rik, A830080H02Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Behavior/neurological

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



decreased locomotor activity	6 supporting datasets	Gigyf2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.34x10^-7
decreased exploration in new environment	2 supporting datasets	Gigyf2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.36x10^-6
increased red blood cell distribution width	1 supporting dataset	Gigyf2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.95x10^-7
decreased erythrocyte cell number	1 supporting dataset	Gigyf2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	9.94x10^-7
increased fasting circulating glucose level	1 supporting dataset	Gigyf2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.99x10^-6
decreased hemoglobin content	1 supporting dataset	Gigyf2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.53x10^-9
tremors	1 supporting dataset	Gigyf2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.01x10^-5
decreased eosinophil cell number	1 supporting dataset	Gigyf2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.79x10^-5
increased circulating phosphate level	1 supporting dataset	Gigyf2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.16x10^-6
increased spleen weight	1 supporting dataset	Gigyf2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.56x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gigyf2.

Associated images

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Histopathology

There is no histopathology data found for Gigyf2.

IMPC related publications

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External links

No external links available for Gigyf2.

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*Gigyf2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Gigyf2^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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