Trp53bp2 | transformation related protein 53 binding protein 2
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Behavior/neurological Mortality/aging
15 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
21Embryo tissues
| increased circulating aspartate transaminase level | 1 supporting dataset | Trp53bp2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 3.25x10-8 | ||
| hyperactivity | 4 supporting datasets | Trp53bp2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 9.88x10-6 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Trp53bp2tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Trp53bp2tm1b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Trp53bp2tm1b(EUCOMM)Hmgu | homozygote | E12.5 | N/A * | ||
| increased hemoglobin content | 1 supporting dataset | Trp53bp2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 6.88x10-5 |
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External links
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| Trp53bp2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Trp53bp2tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |