Sfxn1 | sideroflexin 1

GeneMGI:2137677Synonyms: A930015P12Rik, 2810002O05Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Behavior/neurological

14 No significant impact

7 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues

Phenotypes

increased fasting circulating glucose level1 supporting datasetSfxn1tm1b(EUCOMM)WtsihomozygoteEarly adult8.79x10-6 
decreased grip strength1 supporting datasetSfxn1tm1b(EUCOMM)WtsihomozygoteEarly adult1.5x10-6 
thrombocytosis1 supporting datasetSfxn1tm1b(EUCOMM)WtsihomozygoteEarly adult3.2x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Sfxn1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Sfxn1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Sfxn1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Sfxn1tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Sfxn1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Sfxn1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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