Pom121 | nuclear pore membrane protein 121

GeneMGI:2137624Synonyms: 2610027A18Rik

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Integument Vision/eye Mortality/aging

17 No significant impact

4 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:50Adult tissues
62Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsPom121tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetPom121tm1b(EUCOMM)WtsihomozygoteE9.5N/A * 
decreased total retina thickness1 supporting datasetPom121tm1b(EUCOMM)WtsiheterozygoteEarly adult7.6x10-6 
abnormal coat appearance1 supporting datasetPom121tm1b(EUCOMM)WtsiheterozygoteEarly adult4.2x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pom121tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Pom121tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Pom121tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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