Baiap2 | brain-specific angiogenesis inhibitor 1-associated protein 2

GeneMGI:2137336Synonyms: IRSp53

Physiological systems

22 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Hematopoietic system Mortality/aging

17 No significant impact

2 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
51Embryo tissues

Phenotypes

abnormal testis morphology1 supporting datasetBaiap2tm1b(KOMP)WtsiheterozygoteEarly adultN/A * 
thrombocytopenia1 supporting datasetBaiap2tm1b(KOMP)WtsiheterozygoteEarly adult1.42x10-5 
preweaning lethality, incomplete penetrance3 supporting datasetsBaiap2tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
edema1 supporting datasetBaiap2tm1b(KOMP)WtsihomozygoteE15.5N/A * 
decreased circulating calcium level1 supporting datasetBaiap2tm1b(KOMP)WtsiheterozygoteEarly adult2.23x10-6 
small testis1 supporting datasetBaiap2tm1b(KOMP)WtsiheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Baiap2tm119226(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Baiap2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Baiap2tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Baiap2tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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