Mrpl3 | mitochondrial ribosomal protein L3

GeneMGI:2137204Synonyms: dcr, 5930422H18Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



increased mean corpuscular hemoglobin concentration	1 supporting dataset	Mrpl3^em1(IMPC)J	heterozygote	Early adult	7.78x10^-5
increased circulating bilirubin level	1 supporting dataset	Mrpl3^em1(IMPC)J	heterozygote	Early adult	5.72x10^-5
increased hemoglobin content	1 supporting dataset	Mrpl3^em1(IMPC)J	heterozygote	Early adult	8.25x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Mrpl3^em1(IMPC)J	homozygote	E9.5	N/A ^*
increased circulating alkaline phosphatase level	1 supporting dataset	Mrpl3^em1(IMPC)J	heterozygote	Early adult	3.8x10^-18
preweaning lethality, complete penetrance	1 supporting dataset	Mrpl3^em1(IMPC)J	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mrpl3.

Associated images

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Histopathology

There is no histopathology data found for Mrpl3.

IMPC related publications

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External links

No external links available for Mrpl3.

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*Mrpl3^em1(IMPC)J*	Exon Deletion	‌	mouse
*Mrpl3^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Mrpl3^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mrpl3^{tm3e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Mrpl3^{tm4a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mrpl3^{tm4e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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