Hadhb | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

GeneMGI:2136381Synonyms: Mtpb, 4930479F15Rik

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

17 No significant impact

5 Not tested

Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased fasting circulating glucose level1 supporting datasetHadhbem1(IMPC)BayheterozygoteEarly adult5.55x10-5 
preweaning lethality, incomplete penetrance3 supporting datasetsHadhbem1(IMPC)BayhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Hadhbem1(IMPC)BayExon Deletionmouse
Hadhbtm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Hadhbtm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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