Klhl1 | kelch-like 1

Physiological systems

22 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

14 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged thymus	1 supporting dataset	Klhl1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Klhl1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Klhl1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Klhl1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged epididymis	1 supporting dataset	Klhl1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal epididymis morphology	1 supporting dataset	Klhl1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Klhl1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
small spleen	1 supporting dataset	Klhl1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased exploration in new environment	1 supporting dataset	Klhl1^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.46x10^-5
abnormal spine curvature	1 supporting dataset	Klhl1^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.38x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Klhl1.

Associated images

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Histopathology

There is no histopathology data found for Klhl1.

IMPC related publications

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External links

No external links available for Klhl1.

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*Klhl1^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Klhl1^{tm41806(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Klhl1^{tm41806(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes