Cpn1 | carboxypeptidase N, polypeptide 1

GeneMGI:2135874Synonyms: 0610011F20Rik, CPN, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

15 No significant impact

7 Not tested

Gene metrics:2Significant phenotypes
1Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

decreased grip strength4 supporting datasetsCpn1tm1b(KOMP)WtsihomozygoteEarly adult2.4x10-10 
increased circulating calcium level1 supporting datasetCpn1tm1b(KOMP)WtsihomozygoteEarly adult1.12x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cpn1tm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Cpn1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Cpn1tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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