Klf7 | Kruppel-like transcription factor 7 (ubiquitous)

GeneMGI:1935151Synonyms: 9830124P08Rik

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological Skeleton Mortality/aging

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Zygosity:

Phy. System:



hyperactivity	8 supporting datasets	Klf7^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.45x10^-19
decreased circulating serum albumin level	1 supporting dataset	Klf7^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	5.78x10^-11
persistence of hyaloid vascular system	1 supporting dataset	Klf7^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.72x10^-5
abnormal vertebrae morphology	1 supporting dataset	Klf7^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.26x10^-5
increased circulating aspartate transaminase level	1 supporting dataset	Klf7^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.76x10^-6
increased mean platelet volume	1 supporting dataset	Klf7^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	5.47x10^-9
impaired righting response	1 supporting dataset	Klf7^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.63x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Klf7^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Klf7.

Associated images

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Histopathology

There is no histopathology data found for Klf7.

IMPC related publications

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External links

No external links available for Klf7.

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*Klf7^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Klf7^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Klf7^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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