Kars1 | lysyl-tRNA synthetase 1

GeneMGI:1934754Synonyms: LysRS, D8Ertd698e, +2 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Behavior/neurological Mortality/aging

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

8Associated diseases

Expression examined in:49Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Kars1^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
tremors	1 supporting dataset	Kars1^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	7.18x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Kars1^{tm2b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Kars1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Kars1.

IMPC related publications

Loading...

External links

No external links available for Kars1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Kars1^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Kars1^{tm2b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Kars1^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

My Genes