Kcnn1 | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1

GeneMGI:1933993Synonyms: SK1

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Adipose tissue Hematopoietic system Skeleton

16 No significant impact

5 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

increased total body fat amount1 supporting datasetKcnn1tm1b(KOMP)WtsihomozygoteLate adult7.11x10-6 
increased red blood cell distribution width1 supporting datasetKcnn1tm1b(KOMP)WtsihomozygoteLate adult2.79x10-5 
decreased bone mineral density1 supporting datasetKcnn1tm1b(KOMP)WtsihomozygoteLate adult7.35x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Kcnn1tm186291(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Kcnn1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Kcnn1tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Kcnn1tm1e(KOMP)WtsiTargeted, non-conditional allelees cell

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