Ptov1 | prostate tumor over expressed gene 1

GeneMGI:1933946Synonyms: Gcap3, 1110030G05Rik

Physiological systems

18 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Growth/size/body region Limbs/digits/tail Digestive/alimentary Mortality/aging Craniofacial Cardiovascular system

10 No significant impact

6 Not tested

Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsPtov1em1(IMPC)BayhomozygoteEarly adultN/A * 
abnormal body wall morphology1 supporting datasetPtov1em1(IMPC)BayhomozygoteE18.5N/A * 
hemorrhage1 supporting datasetPtov1em1(IMPC)BayhomozygoteE18.5N/A * 
polydactyly1 supporting datasetPtov1em1(IMPC)BayhomozygoteE18.5N/A * 
abnormal embryo size1 supporting datasetPtov1em1(IMPC)BayhomozygoteE18.5N/A * 
edema1 supporting datasetPtov1em1(IMPC)BayhomozygoteE18.5N/A * 
abnormal facial morphology2 supporting datasetsPtov1em1(IMPC)BayhomozygoteE18.5N/A * 
cleft palate1 supporting datasetPtov1em1(IMPC)BayhomozygoteE18.5N/A * 
facial cleft1 supporting datasetPtov1em1(IMPC)BayhomozygoteE18.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ptov1em1(IMPC)BayExon Deletionmouse
Ptov1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ptov1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ptov1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Ptov1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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