Btbd2 | BTB domain containing 2

GeneMGI:1933831Synonyms: 4930512K17Rik, 2610037C03Rik

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Liver/biliary system Hematopoietic system Behavior/neurological

15 No significant impact

4 Not tested

Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged lymph nodes1 supporting datasetBtbd2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal liver morphology1 supporting datasetBtbd2em1(IMPC)MbphomozygoteEarly adultN/A * 
increased circulating calcium level1 supporting datasetBtbd2em1(IMPC)MbphomozygoteEarly adult9.13x10-5 
increased mean corpuscular volume1 supporting datasetBtbd2em1(IMPC)MbphomozygoteEarly adult5.32x10-5 
abnormal lymph node morphology1 supporting datasetBtbd2em1(IMPC)MbphomozygoteEarly adultN/A * 
limb grasping1 supporting datasetBtbd2em1(IMPC)MbphomozygoteEarly adult2.7x10-5 
small liver1 supporting datasetBtbd2em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Btbd2em1(IMPC)MbpExon Deletionmouse
Btbd2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Btbd2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Btbd2tm83933(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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