Jam2 | junction adhesion molecule 2

GeneMGI:1933820Synonyms: Jcam2, 2410167M24Rik, +3 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Vision/eye Cardiovascular system

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:48Adult tissues

46Embryo tissues

Phenotypes

Phy. System:



increased circulating sodium level	1 supporting dataset	Jam2^{tm1.1(KOMP)Mbp}	homozygote	Early adult	1.47x10^-7
abnormal retina morphology	1 supporting dataset	Jam2^{tm1.1(KOMP)Mbp}	homozygote	Early adult	4.19x10^-7
increased heart weight	1 supporting dataset	Jam2^{tm1.1(KOMP)Mbp}	homozygote	Early adult	5.1x10^-5
increased circulating potassium level	1 supporting dataset	Jam2^{tm1.1(KOMP)Mbp}	homozygote	Early adult	7.57x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Jam2.

Associated images

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Histopathology

There is no histopathology data found for Jam2.

IMPC related publications

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External links

No external links available for Jam2.

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*Jam2^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*Jam2^{tm1.1(KOMP)Mbp}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

My Genes