Btbd1 | BTB domain containing 1

GeneMGI:1933765Synonyms: 1190005H08Rik

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system Renal/urinary system

17 No significant impact

3 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:78Adult tissues
36Embryo tissues

Phenotypes

increased CD8-positive, naive alpha-beta T cell number1 supporting datasetBtbd1tm1a(KOMP)WtsihomozygoteEarly adult4.24x10-5 
decreased circulating total protein level1 supporting datasetBtbd1tm1a(KOMP)WtsihomozygoteEarly adult1.84x10-5 
single kidney1 supporting datasetBtbd1tm1a(KOMP)WtsihomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetBtbd1tm1a(KOMP)WtsihomozygoteEarly adultN/A * 
increased CD4-positive NK T cell number1 supporting datasetBtbd1tm1a(KOMP)WtsihomozygoteEarly adult9.43x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Btbd1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Btbd1tm1e(KOMP)WtsiTargeted, non-conditional allelees cell

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