Actl6b | actin-like 6B

GeneMGI:1933548Synonyms: Actl6, ArpNa, +1 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Reproductive system Hearing/vestibular/ear Behavior/neurological Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal auditory brainstem response	3 supporting datasets	Actl6b^em1(IMPC)J	heterozygote	Early adult	4.23x10^-5
female infertility	1 supporting dataset	Actl6b^em1(IMPC)J	homozygote	Early adult	N/A ^*
preweaning lethality, incomplete penetrance	1 supporting dataset	Actl6b^em1(IMPC)J	homozygote	Early adult	N/A ^*
hyperactivity	1 supporting dataset	Actl6b^em1(IMPC)J	heterozygote	Early adult	8.43x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Actl6b.

Associated images

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Histopathology

There is no histopathology data found for Actl6b.

IMPC related publications

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External links

No external links available for Actl6b.

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*Actl6b^em1(IMPC)J*	Exon Deletion	‌	mouse
*Actl6b^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Actl6b^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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