Lactb | lactamase, beta

GeneMGI:1933395Synonyms: Mrpl56

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Vision/eye Cardiovascular system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating cholesterol level	1 supporting dataset	Lactb^{tm1.1(KOMP)Mbp}	homozygote	Early adult	8.25x10^-8
abnormal retina blood vessel morphology	1 supporting dataset	Lactb^{tm1.1(KOMP)Mbp}	homozygote	Early adult	9.25x10^-9
abnormal retina morphology	1 supporting dataset	Lactb^{tm1.1(KOMP)Mbp}	homozygote	Early adult	9.09x10^-8
abnormal retina vasculature morphology	1 supporting dataset	Lactb^{tm1.1(KOMP)Mbp}	homozygote	Early adult	6.72x10^-10
decreased circulating HDL cholesterol level	1 supporting dataset	Lactb^{tm1.1(KOMP)Mbp}	homozygote	Early adult	6.76x10^-6
enlarged heart	1 supporting dataset	Lactb^{tm1.1(KOMP)Mbp}	homozygote	Early adult	N/A ^*
increased circulating bilirubin level	1 supporting dataset	Lactb^{tm1.1(KOMP)Mbp}	homozygote	Early adult	4.35x10^-5
persistence of hyaloid vascular system	1 supporting dataset	Lactb^{tm1.1(KOMP)Mbp}	homozygote	Early adult	2.87x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lactb.

Associated images

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Histopathology

There is no histopathology data found for Lactb.

IMPC related publications

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External links

No external links available for Lactb.

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*Lactb^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*Lactb^{tm1.1(KOMP)Mbp}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

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