Bicc1 | BicC family RNA binding protein 1
Physiological systems
22 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Behavior/neurological Mortality/aging Cardiovascular system Renal/urinary system
16 No significant impact
2 Not tested
Data collections
Gene metrics:12Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
abnormal heart morphology | 1 supporting dataset | Bicc1em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
abnormal heart looping | 1 supporting dataset | Bicc1em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
abnormal placenta vasculature | 1 supporting dataset | Bicc1em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Bicc1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
edema | 1 supporting dataset | Bicc1em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
decreased locomotor activity | 1 supporting dataset | Bicc1em1(IMPC)Mbp | heterozygote | Early adult | 1.36x10-8 | ||
abnormal blood vessel morphology | 1 supporting dataset | Bicc1em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
preweaning lethality, incomplete penetrance | 2 supporting datasets | Bicc1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
small kidney | 1 supporting dataset | Bicc1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
abnormal placenta morphology | 1 supporting dataset | Bicc1em1(IMPC)Mbp | homozygote | E15.5 | N/A * |
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External links
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Bicc1em1(IMPC)Mbp | Exon Deletion | | mouse |
Bicc1tm43183(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
Bicc1tm43183(L1L2_gt1) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |