Trim8 | tripartite motif-containing 8

GeneMGI:1933302Synonyms: Rnf27, GERP

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Hematopoietic system

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased mean corpuscular hemoglobin1 supporting datasetTrim8em1(IMPC)WtsihomozygoteEarly adult3.55x10-9 
decreased circulating serum albumin level1 supporting datasetTrim8em1(IMPC)WtsihomozygoteEarly adult1.51x10-5 
decreased circulating cholesterol level1 supporting datasetTrim8em1(IMPC)WtsihomozygoteEarly adult1.52x10-7 
decreased circulating HDL cholesterol level1 supporting datasetTrim8em1(IMPC)WtsihomozygoteEarly adult3.09x10-6 
increased body length1 supporting datasetTrim8em1(IMPC)WtsihomozygoteEarly adult8.46x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Trim8em1(IMPC)WtsiDeletionmouse

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