Gtf2a1 | general transcription factor II A, 1

GeneMGI:1933277Synonyms: TfIIAa/b, Tfiia1, +3 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Adipose tissue Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Gtf2a1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
increased total body fat amount	1 supporting dataset	Gtf2a1^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	2.76x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gtf2a1.

Associated images

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Histopathology

There is no histopathology data found for Gtf2a1.

IMPC related publications

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External links

No external links available for Gtf2a1.

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*Gtf2a1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Gtf2a1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Gtf2a1^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Gtf2a1^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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