Chrdl1 | chordin-like 1

GeneMGI:1933172Synonyms: ventroptin-alpha, Nrln1, +3 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Cardiovascular system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

prolonged QRS complex duration1 supporting datasetChrdl1em1(IMPC)HhomozygoteLate adult1.14x10-5 
increased fasting circulating glucose level1 supporting datasetChrdl1em1(IMPC)HhomozygoteEarly adult9.19x10-6 
hyperactivity1 supporting datasetChrdl1em1(IMPC)HhemizygoteLate adult9.63x10-5 
hyperactivity1 supporting datasetChrdl1em1(IMPC)HhomozygoteEarly adult1.58x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Chrdl1em1(IMPC)HExon Deletionmouse
Chrdl1em2(IMPC)HExon Deletionmouse
Chrdl1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Chrdl1tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Chrdl1tm2e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Chrdl1tm41090(L1L2_st0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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