Sacm1l | SAC1 suppressor of actin mutations 1-like (yeast)
Physiological systems
22 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Reproductive system Endocrine/exocrine gland Behavior/neurological Mortality/aging
18 No significant impact
2 Not tested
Data collections
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
30Embryo tissues
decreased thigmotaxis | 2 supporting datasets | Sacm1ltm1b(KOMP)Wtsi | heterozygote | Early adult | 2.01x10-5 | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Sacm1ltm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
enlarged epididymis | 1 supporting dataset | Sacm1ltm1b(KOMP)Wtsi | heterozygote | Early adult | N/A * | ||
abnormal epididymis morphology | 1 supporting dataset | Sacm1ltm1b(KOMP)Wtsi | heterozygote | Early adult | N/A * | ||
embryonic lethality prior to organogenesis | 1 supporting dataset | Sacm1ltm1b(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
hyperactivity | 1 supporting dataset | Sacm1ltm1b(KOMP)Wtsi | heterozygote | Early adult | 4.89x10-5 | ||
small testis | 1 supporting dataset | Sacm1ltm1b(KOMP)Wtsi | heterozygote | Early adult | N/A * | ||
embryonic lethality prior to tooth bud stage | 1 supporting dataset | Sacm1ltm1b(KOMP)Wtsi | homozygote | E12.5 | N/A * | ||
abnormal testis morphology | 1 supporting dataset | Sacm1ltm1b(KOMP)Wtsi | heterozygote | Early adult | N/A * | ||
abnormal behavior | 1 supporting dataset | Sacm1ltm1b(KOMP)Wtsi | heterozygote | Early adult | 2.01x10-5 |
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External links
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Sacm1ltm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Sacm1ltm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Sacm1ltm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Sacm1ltm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |