Tusc3 | tumor suppressor candidate 3

GeneMGI:1933134

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Embryo Growth/size/body region Vision/eye Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



persistence of hyaloid vascular system	1 supporting dataset	Tusc3^em1(IMPC)J	heterozygote	Early adult	2.19x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Tusc3^em1(IMPC)J	homozygote	Early adult	N/A ^*
abnormal embryo size	1 supporting dataset	Tusc3^em1(IMPC)J	homozygote	E18.5	N/A ^*
abnormal body wall morphology	1 supporting dataset	Tusc3^em1(IMPC)J	homozygote	E18.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tusc3.

Associated images

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Histopathology

There is no histopathology data found for Tusc3.

IMPC related publications

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External links

No external links available for Tusc3.

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*Tusc3^em1(IMPC)J*	Intra-exon deletion	‌	mouse
*Tusc3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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