Gpr146 | G protein-coupled receptor 146

GeneMGI:1933113Synonyms: PGR8

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Behavior/neurological

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



decreased hemoglobin content	1 supporting dataset	Gpr146^em1(IMPC)H	homozygote	Late adult	5.92x10^-10
increased red blood cell distribution width	1 supporting dataset	Gpr146^em1(IMPC)H	homozygote	Late adult	1.81x10^-14
decreased mean corpuscular volume	1 supporting dataset	Gpr146^em1(IMPC)H	homozygote	Late adult	3.77x10^-13
decreased circulating cholesterol level	1 supporting dataset	Gpr146^em1(IMPC)H	homozygote	Early adult	7.86x10^-5
decreased circulating triglyceride level	1 supporting dataset	Gpr146^em1(IMPC)H	homozygote	Early adult	8.73x10^-8
decreased circulating cholesterol level	1 supporting dataset	Gpr146^em1(IMPC)H	homozygote	Late adult	2.74x10^-5
decreased mean corpuscular hemoglobin	1 supporting dataset	Gpr146^em1(IMPC)H	homozygote	Late adult	8.02x10^-18
decreased circulating iron level	1 supporting dataset	Gpr146^em1(IMPC)H	homozygote	Late adult	4.14x10^-17
increased spleen weight	1 supporting dataset	Gpr146^em1(IMPC)H	homozygote	Late adult	2.4x10^-8
decreased mean corpuscular hemoglobin concentration	1 supporting dataset	Gpr146^em1(IMPC)H	homozygote	Late adult	2.01x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gpr146.

Associated images

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Histopathology

There is no histopathology data found for Gpr146.

IMPC related publications

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External links

No external links available for Gpr146.

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*Gpr146^em1(IMPC)H*	Indel	‌	mouse
*Gpr146^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Gpr146^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	es cell

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