Celf4 | CUGBP, Elav-like family member 4

GeneMGI:1932407Synonyms: C130060B05Rik, Brunol4, +3 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased circulating insulin level	1 supporting dataset	Celf4^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	6.19x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Celf4^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
impaired glucose tolerance	1 supporting dataset	Celf4^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	6.71x10^-6
decreased circulating cholesterol level	1 supporting dataset	Celf4^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	7.15x10^-5
decreased circulating calcium level	1 supporting dataset	Celf4^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.51x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Celf4.

Associated images

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Histopathology

There is no histopathology data found for Celf4.

IMPC related publications

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External links

No external links available for Celf4.

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*Celf4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Celf4^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Celf4^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell

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