Egln3 | egl-9 family hypoxia-inducible factor 3

GeneMGI:1932288Synonyms: SM-20, Hif-p4h-3, +2 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Nervous system Vision/eye Cardiovascular system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:50Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal sinus arrhythmia	1 supporting dataset	Egln3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.07x10^-6
abnormal optic disk morphology	1 supporting dataset	Egln3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.59x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Egln3.

Associated images

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Histopathology

There is no histopathology data found for Egln3.

IMPC related publications

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External links

No external links available for Egln3.

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*Egln3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Egln3^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Egln3^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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