Tnxb | tenascin XB

GeneMGI:1932137Synonyms: Tnx, TN-MHC

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Skeleton Cardiovascular system

13 No significant impact

5 Not tested

Gene metrics:5Significant phenotypes
4Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

enlarged spleen1 supporting datasetTnxbtm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
decreased bone mineral content1 supporting datasetTnxbtm1b(EUCOMM)HmguhomozygoteEarly adult7.38x10-5 
decreased circulating alkaline phosphatase level1 supporting datasetTnxbtm1b(EUCOMM)HmguhomozygoteEarly adult7.24x10-5 
decreased blood urea nitrogen level1 supporting datasetTnxbtm1b(EUCOMM)HmguhomozygoteEarly adult4.81x10-5 
enlarged heart1 supporting datasetTnxbtm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tnxbtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Tnxbtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Tnxbtm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Tnxbtm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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