Btnl4 | butyrophilin-like 4

GeneMGI:1932036Synonyms: Btn3a3, EG632126, +1 more

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Integument Growth/size/body region Hematopoietic system Cardiovascular system

12 No significant impact

7 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal skin morphology1 supporting datasetBtnl4em1(IMPC)TcphomozygoteEarly adultN/A * 
enlarged spleen1 supporting datasetBtnl4em1(IMPC)TcphomozygoteEarly adultN/A * 
prolonged RR interval1 supporting datasetBtnl4em1(IMPC)TcphomozygoteEarly adult9.88x10-6 
prolonged QT interval1 supporting datasetBtnl4em1(IMPC)TcphomozygoteEarly adult2.02x10-5 
prolonged ST segment1 supporting datasetBtnl4em1(IMPC)TcphomozygoteEarly adult2.29x10-5 
enlarged lymph nodes1 supporting datasetBtnl4em1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Btnl4em1(IMPC)TcpInter-exon deletionmouse
Btnl4tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell

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