Dnaja2 | DnaJ heat shock protein family (Hsp40) member A2

GeneMGI:1931882Synonyms: DNJ3, HIRIP4, +4 more

Physiological systems

22 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Reproductive system Vision/eye Behavior/neurological Mortality/aging

18 No significant impact

2 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal vitreous body morphology1 supporting datasetDnaja2em1(IMPC)MbpheterozygoteEarly adult7.3x10-5 
female infertility1 supporting datasetDnaja2em1(IMPC)MbphomozygoteEarly adultN/A * 
preweaning lethality, incomplete penetrance3 supporting datasetsDnaja2em1(IMPC)MbphomozygoteEarly adultN/A * 
no spontaneous movement1 supporting datasetDnaja2em1(IMPC)MbphomozygoteE18.5N/A * 
no spontaneous movement1 supporting datasetDnaja2em1(IMPC)MbpheterozygoteE18.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dnaja2em1(IMPC)MbpExon Deletionmouse
Dnaja2tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Dnaja2tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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