Pum2 | pumilio RNA-binding family member 2

GeneMGI:1931751Synonyms: Pumm2, 5730503J23Rik

Physiological systems

16 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

11 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased startle reflex	1 supporting dataset	Pum2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1x10^-5
decreased total body fat amount	1 supporting dataset	Pum2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.75x10^-5
increased bone mineral content	1 supporting dataset	Pum2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.8x10^-11
increased mean platelet volume	1 supporting dataset	Pum2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.42x10^-5
increased lean body mass	1 supporting dataset	Pum2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.77x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pum2.

Associated images

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Histopathology

There is no histopathology data found for Pum2.

IMPC related publications

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External links

No external links available for Pum2.

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*Pum2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pum2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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