Dbr1 | debranching RNA lariats 1
GeneMGI:1931520
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Mortality/aging Renal/urinary system
15 No significant impact
5 Not tested
Data collections
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues
| abnormal lens morphology | 1 supporting dataset | Dbr1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 5.78x10-7 | ||
| decreased urine magnesium level | 1 supporting dataset | Dbr1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.81x10-61 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Dbr1tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Dbr1tm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * |
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External links
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| Dbr1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Dbr1tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Dbr1tm78661(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |