Slc35b4 | solute carrier family 35, member B4

GeneMGI:1931249Synonyms: 4930474D06Rik

Physiological systems

22 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Embryo Growth/size/body region Nervous system Behavior/neurological Mortality/aging Cardiovascular system

16 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

30Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic growth retardation	1 supporting dataset	Slc35b4^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
hyperactivity	3 supporting datasets	Slc35b4^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	3.14x10^-10
abnormal embryo size	1 supporting dataset	Slc35b4^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
abnormal forebrain development	1 supporting dataset	Slc35b4^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Slc35b4^{tm1.1(KOMP)Vlcg}	heterozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Slc35b4^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal midbrain development	1 supporting dataset	Slc35b4^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
abnormal embryo size	1 supporting dataset	Slc35b4^{tm1.1(KOMP)Vlcg}	heterozygote	E9.5	N/A ^*
increased heart weight	1 supporting dataset	Slc35b4^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	3.61x10^-6
abnormal heart morphology	1 supporting dataset	Slc35b4^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Slc35b4.

Associated images

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Histopathology

There is no histopathology data found for Slc35b4.

IMPC related publications

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External links

No external links available for Slc35b4.

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*Slc35b4^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Slc35b4^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Slc35b4^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Slc35b4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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