Rrad | Ras-related associated with diabetes

GeneMGI:1930943Synonyms: Rad, REM3

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Hematopoietic system Cardiovascular system

14 No significant impact

6 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
52Embryo tissues

Phenotypes

increased heart rate1 supporting datasetRradtm1.1(KOMP)VlcghomozygoteEarly adult6.45x10-6 
shortened ST segment1 supporting datasetRradtm1.1(KOMP)VlcghomozygoteEarly adult8.53x10-6 
shortened RR interval1 supporting datasetRradtm1.1(KOMP)VlcghomozygoteEarly adult6.03x10-5 
increased circulating potassium level1 supporting datasetRradtm1.1(KOMP)VlcghomozygoteEarly adult2.94x10-5 
increased heart weight1 supporting datasetRradtm1.1(KOMP)VlcghomozygoteEarly adult1.01x10-5 
increased circulating alkaline phosphatase level1 supporting datasetRradtm1.1(KOMP)VlcghomozygoteEarly adult2.91x10-10 
increased mean corpuscular hemoglobin1 supporting datasetRradtm1.1(KOMP)VlcghomozygoteEarly adult1.68x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rradtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Rradtm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Rradtm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Rradtm278441(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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