Spz1 | spermatogenic leucine zipper 1

GeneMGI:1930801Synonyms: 1700027M20Rik

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Vision/eye Hematopoietic system Cardiovascular system Renal/urinary system

11 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:15Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased red blood cell distribution width1 supporting datasetSpz1em1(IMPC)MbphomozygoteEarly adult7.34x10-8 
enlarged ovary1 supporting datasetSpz1em1(IMPC)MbphomozygoteEarly adultN/A * 
increased neutrophil cell number1 supporting datasetSpz1em1(IMPC)MbphomozygoteEarly adult6.41x10-6 
enlarged kidney1 supporting datasetSpz1em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal skin morphology2 supporting datasetsSpz1em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal kidney morphology2 supporting datasetsSpz1em1(IMPC)MbphomozygoteEarly adultN/A * 
urinary bladder obstruction1 supporting datasetSpz1em1(IMPC)MbphomozygoteEarly adultN/A * 
small kidney1 supporting datasetSpz1em1(IMPC)MbphomozygoteEarly adultN/A * 
increased heart weight2 supporting datasetsSpz1em1(IMPC)MbphomozygoteEarly adult6.03x10-7 
abnormal retina morphology1 supporting datasetSpz1em1(IMPC)MbphomozygoteEarly adult5.03x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Spz1em1(IMPC)MbpWhole-gene deletionmouse

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